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In addition, researchers found the rate of CD4 cell decline occurred twice as fast in individuals with the VB variant, placing them at higher risk of developing AIDS more rapidly. Researchers then analyzed data from a cohort of more than 6,700 HIV positive patients in the country and identified an additional 92 people with the variant.Īccording to the study, these individuals had a viral load that was between 3.5 and 5.5 times higher than average. The VB variant was first identified in 17 HIV positive individuals - 15 of whom were from the Netherlands - from the BEEHIVE project, an ongoing study that collects samples from across Europe and Uganda. The study notes the age, sex and suspected mode of transmission for these 109 individuals were all typical for people living with HIV in the Netherlands. Researchers analyzed 109 patients with the VB variant and compared them to patients of other, subtype-B HIV strains. The findings were published Thursday in Science, the peer-reviewed academic journal of the American Association for the Advancement of Science (AAAS).
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"This means that the virulence normalized by the amount of virus… which for HIV is heritable is much higher for the VB variant," the study's authors wrote. CD4 cells, also known as T-cells, are a subset of white blood cells that fight infection and protect the body's immune system. The study found that patients infected with the variant of subtype-B HIV-1, dubbed the VB variant, showed "significant" differences before antiretroviral treatment compared with individuals infected with other HIV variants.Īccording to the study, individuals with the VB variant reported a higher level of the virus in their blood and showed a CD4 cell count that declined twice as fast as those infected with other strains. Demographic information is being collected for research purposes only and will be kept strictly confidential.Researchers in the Netherlands have discovered a "highly virulent variant" of HIV that causes a more rapid decline in immune system strength and can result in more damaging health outcomes if not treated early. The test is also available in Simplified Chinese, Traditional Chinese, Arabic, Italian, Malay, French, Spanish, German, Hungarian, Dutch, Korean, and Japanese.īefore we get to the test itself, we'll ask you a few basic questions about yourself. If you are conducting research and would like to collect raw data for a group that is taking this test - for a business, research study, classroom activity, or other purpose - please see our Group Testing Instructions. This test will show you where you are on the Sexual Orientation Continuum, and it will also calculate your Sexual Orientation Range, an estimate of how much flexibility you have in expressing your sexual orientation. Robert Epstein, one of America's most distinguished research psychologists (follow on Twitter at The test has been empirically validated with a sample of more than 600,000 people in 219 countries and territories.Īlthough many people believe that everyone is either "straight" (heterosexual) or "gay" (homosexual), sexual orientation actually exists on a continuum. You are about to take the Epstein Sexual Orientation Inventory (ESOI), a test of sexual orientation designed by Dr.